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KMID : 0613820040140010188
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Journal of Life Science
2004 Volume.14 No. 1 p.188 ~ p.192
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Cross-Resistance to Toluene and Heat in Micrococcus sp. BCNU 121
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Joo Woo-Hong
Han Su-Ji
Choi Yong-Lark
Jeong Young-kee
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Abstract
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Toluene tolerance and thermotolerance in Gram-positive organic solvent resistant bacterium Micrococcus sp. BCNU 121 has been studied. Exposure to a sub-lethal temperature or a sub-lethal concentration of toluene conferred protection to subsequent challenges with a killing temperature or a lethal concentration of toluene, respectively. Pretreatment of Micrococcus sp. BCNU 121 with sub-lethal concentrations of toluene induced adaptative protection against heat shock. Moreover, temperature-adaptative cells also showed cross-resistance to lethal doses of toluene. These data suggested a cross-regulation between toluene tolerance and heat shock response.
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KEYWORD
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Micrococcus sp., cross-resistance, cross-protection, solvent-resistance
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